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New Research "UNCOVERS" Hidden Objects in High Resolution

08-11-22

Imagine driving home after a long day at work. Suddenly, a car careens out of an obscured side street and turns right in front of you. Luckily, your autonomous car saw this vehicle long before it came within your line of sight and slowed to avoid a crash. This might seem like magic, but a novel technique developed in the laboratory of Changhuei Yang, Thomas G. Myers Professor of Electrical Engineering, Bioengineering, and Medical Engineering; Investigator, Heritage Medical Research Institute, could bring it closer to a reality. "We can see all the traffic on the crossroads with this method. This might help the cars to foresee the potential danger that one is not able to see directly." explains electrical engineering graduate student Ruizhi Cao. [Caltech story]

Tags: EE research highlights Changhuei Yang MedE Ruizhi Cao

New Caltech Center for Sensing to Intelligence (S2I) Launches Collaboration with Industry Partner

12-02-21

The Caltech Center for Sensing to Intelligence (S2I) has announced that, in collaboration with Rockley Photonics, a photonics-based health monitoring and communications solutions company, it will allocate $1.5 million in research grants over the next three years to jumpstart efforts to combine sensors with artificial intelligence. "We would like to have sensors in every device these days, generating a huge amount of data," says Azita Emami, Andrew and Peggy Cherng Professor of Electrical Engineering and Medical Engineering and the director of S2I. "But it's difficult to extract the most important information from the mountains of data they create." [Caltech story]

Tags: APhMS EE Changhuei Yang MedE CMS Azita Emami CNS Animashree Anandkumar Alireza Marandi Katie Bouman

Changhuei Yang Named to National Academy of Inventors

12-10-20

Changhuei Yang, Thomas G. Myers Professor of Electrical Engineering, Bioengineering, and Medical Engineering, has been named fellow of the National Academy of Inventors (NAI). Election as a fellow is the highest professional distinction accorded to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society. The Yang lab develops technologies aimed at transforming the conventional microscope so that it can be used for high-throughput, automated applications. He also works on the use of "time-reversal" techniques to undo the effect of tissue light scattering. [Caltech story] [List of 2020 Fellows]

Tags: EE honors Changhuei Yang MedE

Seeing Through Opaque Media

05-12-20

Changhuei Yang, Thomas G. Myers Professor of Electrical Engineering, Bioengineering, and Medical Engineering, has developed a technique that combines fluorescence and ultrasound to peer through opaque media, such as biological tissue. "We hope that one day this method can be deployed to extend the operating depth of fluorescence microscopy and help image fluorescent labeled cells deep inside living animals," says Yang. [Caltech story]

Tags: EE research highlights Changhuei Yang MedE KNI

Engineered Metasurfaces Replace Adhesive Tape in Specialized Microscope

02-28-18

The latest advance in a new type of optics aimed at improving microscopy started with a game of tennis three years ago between Mooseok Jang a graduate of Professor Changhuei Yang's lab and Yu Horie working with Professor Andrei Faraon. "The hope is that our work will prompt further interest in this area of optics and make this type of microscopy and its advantages feasible for practical, everyday use—not just as a proof of concept," says Josh Brake, a graduate student in Yang's lab who continues to work on the project with Faraon and Yang. [Caltech story]

Tags: EE research highlights Changhuei Yang MedE alumni Andrei Faraon Mooseok Jang APh Yu Horie Josh Brake

Noise-Canceling Optics

10-10-16

Changhuei Yang, Professor of Electrical Engineering, Bioengineering, and Medical Engineering, and colleagues have created the visual analogue of noise-canceling headphones—a camera system that can obtain images of objects obscured by murky media, such as fog or clouds, by canceling out the glare. Their device selectively cancels the scattered light, leaving only the light that is reflected or bounced off the objects and has slipped back through the murk unmolested. [Caltech story]

Tags: EE research highlights Changhuei Yang MedE

Roarke Horstmeyer Wins Charles Wilts Prize

06-07-16

Roarke Horstmeyer, advised by Professor Changhuei Yang is the winner of this year’s Charles Wilts Prize, for his doctoral thesis “Computational microscopy: turning megapixels into gigapixels.” The Charles Wilts Prize is awarded every year to a graduate student in Electrical Engineering for outstanding independent research.

Tags: EE honors Changhuei Yang Wilts Prize Roarke Horstmeyer

 
Popping Microbubbles Help Focus Light Inside the Body

12-03-15

Changhuei Yang, Professor of Electrical Engineering, Bioengineering, and Medical Engineering, and his postdoctoral colleague Dr. Haowen Ruan have developed a novel technique called time-reversed ultrasound microbubble encoded (TRUME) that uses gas-filled microbubbles to focus light inside tissue. "Ultrasound and X-ray techniques can only detect cancer after it forms a mass," Yang says. "But with optical focusing, you could catch cancerous cells while they are undergoing biochemical changes but before they undergo morphological changes." [Caltech story]

Tags: EE research highlights Changhuei Yang MedE health postdocs

Student Research in Biomedical Optics Wins First Place

07-02-15

Electrical Engineering postdoctoral scholar Dr. Haowen Ruan and graduate student Mooseok Jang, who work with Professor Changhuei Yang, have won first place for Best Student Poster Presentation at the Engineering Conferences International (ECI) series entitled “Advances in Optics in Biotechnology, Medicine and Surgery XIV.” Their winning poster demonstrated research in biomedical optics, specifically a novel technique that focuses light inside biological tissue by time-reversing the light encoded through popping of a microbubble. The technique has the potential to enable one to “see” through biological bodies with light.

Tags: EE honors research highlights Changhuei Yang MedE Haowen Ruan Mooseok Jang postdocs

Pushing Microscopy Beyond Standard Limits

07-29-13

Changhuei Yang, Professor of Electrical Engineering and Bioengineering, and colleagues have shown how to make cost-effective, ultra-high-performance microscopes. The final images produced by their new system contain 100 times more information than those produced by conventional microscope platforms. And building upon a conventional microscope, their new system costs only about $200 to implement. This new method could have wide applications not only in digital pathology but also in everything from hematology to wafer inspection to forensic photography. [Caltech Release]

Tags: EE research highlights Changhuei Yang MedE health