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Changhuei Yang Develops "Microscope on a Chip"

07-28-08

Changhuei Yang, Assistant Professor of Electrical Engineering and Bioengineering, and colleagues have turned science fiction into reality with their development of a super-compact high-resolution microscope, small enough to fit on a finger tip. This "microscopic microscope" operates without lenses but has the magnifyingpower of a top-quality optical microscope, can be used in the field to analyze blood samples for malaria or check water supplies for giardia and other pathogens, and can be mass-produced for around $10. 

Tags: EE research highlights Changhuei Yang MedE health

Simona Bordoni and Tapio Schneider Offer New Explanation for Monsoon Development

07-25-08

Tapio Schneider, Associate Professor of Environmental Science and Engineering, has come up with a new explanation for the formation of monsoons. Schneider and colleague Simona Bordoni, who will start as an assistant professor at Caltech in 2009, propose an overhaul of a theory about the cause of the seasonal pattern of heavy winds and rainfall that essentially had held firm for more than 300 years. [Caltech Press Release]

Tags: research highlights ESE Simona Bordoni Tapio Schneider

 
Jeff Snyder and Colleagues Invent New Material that Will Make Cars More Efficient

07-25-08

Caltech Faculty Associate Jeff Snyder and colleagues have invented a new material that will make cars even more efficient by converting heat lost through engine exhaust into electricity. In a paper published July 25 in the journal Science, the scientists describe the unique thermoelectric material, which has twice the efficiency other such materials currently on the market, and works most effectively in the temperature range typical of automobile engines. The same technology could also work in power generators and heat pumps. Read more at www.sciencemag.org.

Tags: APhMS energy research highlights Jeff Snyder

Axel van de Walle Developes Formalism to Represent Structure-property Relationships in Crystals

07-11-08

Axel van de Walle, Assistant Professor of Materials Science, has developed a general formalism to represent structure-property relationships in crystals. It enables the prediction, from a database of quantum mechanical calculations, of anisotropic material properties such as elasticity, piezoelectricity, dielectric constants, etc. As an application, he developed predictive models of anisotropic properties relevant to the design and optimization of III–V semiconductor epitaxial optoelectronic devices. This work was recently highlighted as the cover feature of Nature Materials. [Nature Article] [Commentary]

Tags: APhMS research highlights Axel van de Walle

Melissa Saenz and Christof Koch Show that Sight Recovery After Blindness Offers New Insights on Brain Reorganization

05-29-08

Studies of the brains of blind persons whose sight was partially restored later in life have produced a compelling example of the brain's ability to adapt to new circumstances and rewire and reconfigure itself. The research, conducted by postdoctoral researcher Melissa Saenz along with Christof Koch, the Lois and Victor Troendle Professor of Cognitive and Behavioral Biology and professor of computation and neural systems, and their colleagues, shows that the part of the brain that processes visual information in normal individuals can be co-opted to respond to both visual and auditory information. [Caltech Press Release]

Tags: EE research highlights health Christof Koch postdocs

 
Chemistry of Airborne Particulate—Lung Interactions Revealed by Agustin Colussi and Colleagues

05-26-08

Agustin J. Colussi, senior research associate in environmental science and engineering, and colleagues have found that airborne particulates impair the lungs' naturaldefenses against ozone. Their research focused on what happens when air meets the thin layer of antioxidant-rich fluid that covers our lungs, protecting them from ozone, an air pollutant that pervades major cities. "We found new chemistry at the interfaces separating gases from liquids using a technique that continuously monitors the composition of these interfaces," Colussi says. Under normal physiological conditions, ascorbic acid instantly scavenges ozone, generating innocuous byproducts. However, the researchers discovered that when the fluid is acidic, a pathological condition found in asthmatics, ascorbic acid instead reacts with ozone to form potentially harmful compounds called ozonides.

Tags: research highlights health ESE Agustin Colussi

 
CACR Helps Open the Universe in "WorldWide Telescope"

05-25-08

World Wide Telescope (WWT), a new Microsoft product, combines cosmic imagery and educational content from many sources, including major ground-based sky surveys. A significant portion of the data was processed at Caltech's Center for Advanced Computing Research (CACR). [Caltech Press Release]

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Michael Dickinson Named to the American Academy of Arts and Sciences

04-30-08

Michael Dickinson, Esther M. and Abe M. Zarem Professor of Bioengineering, is among the 190 new Fellows elected to the American Academy of Arts and Sciences this year. Dickinson studies animal physiology and behavior and has become well known for Robofly, a mechanical fly that sprang from his work on the neurobiology and biomechanics of fly locomotion. Throughout his career, Dickinson has used a variety of tools, such as wind tunnels, virtual reality simulators, high-speed video, and giant robotic models, to determine how the poppy seed-sized brains of these tiny insects can rapidly control aerodynamic forces. More than a simple understanding of the material basis for insect flight, Dickinson's studies provide insight into complex systems operating on biological and physical principles: neuronal signaling within brains, the dynamics of unsteady fluid flow, the structural mechanics of composite materials, and the behavior of nonlinear systems are all linked when a fly takes wing. [Caltech Press Release].

Tags: honors research highlights Michael Dickinson AMACAD

Athanassios Siapas and Evgueniy Lubenov Reveal the Driving Factor in the Brain's Self-regulation

04-18-08

Using computer models of neuronal circuits and experiments on live rats, Athanassios Siapas, Assistant Professor of Computation and Neural Systems, and his postdoctoral researcher Evgueniy Lubenov are revealing the curious mechanism by which the brain spontaneously tips itself toward a state balanced between order and chaos. The driving factor in the brain's self-regulation, they say, is the timing of neural pulses. "Networks self-organize to an intermediate state, in between the two extremes," Siapas says.

Tags: EE research highlights health Thanos Siapas postdocs

New Center to Study the Global Environment

04-15-08

To address the complex issue of global climate change from a wide range of disciplines, Ronald and Maxine Linde have established an $18 million endowment for the Ronald and Maxine Linde Center for Global Environmental Science, uniting faculty from chemistry, engineering, geology, environmental science, and other fields. The initiative will help Caltech achieve its vision of having an integrated program in global environmental science, spanning the many disciplines that must make up such a program. Edward Stolper, Caltech's provost, explains that the Linde Center "will provide a central home and focus for researchers and students working on understanding natural variations in and the impact of human activity on the global environment. These are among the most important and most difficult problems facing our society." [Caltech Press Release]

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