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Quantum Entanglement of Photons Doubles Microscope Resolution

05-02-23

Using a "spooky" phenomenon of quantum physics, Caltech researchers have discovered a way to double the resolution of light microscopes. In a paper appearing in the journal Nature Communications, a team led by Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, shows the achievement of a leap forward in microscopy through what is known as quantum entanglement. Quantum entanglement is a phenomenon in which two particles are linked such that the state of one particle is tied to the state of the other particle regardless of whether the particles are anywhere near each other. Albert Einstein famously referred to quantum entanglement as "spooky action at a distance" because it could not be explained by his relativity theory. [Caltech story]

Tags: EE MedE Lihong Wang

Changhao Xu Receives AI4Science Fellowship

04-03-23

Medical Engineering student Changhao Xu has been selected as a recipient of the 2022-2023 AI4Science Fellowship. The AI4Science program recognizes graduate students and postdoctoral scholars that have had a remarkable impact in artificial intelligence and machine learning, and in their application to fields beyond computer science. The awards are selected by a committee of faculty including those from both CMS and beyond. This program is enabled by a partnership with Amazon. The fellowship makes opportunities available to the awardees throughout the year where they can present and meet with researchers at Amazon.

Tags: honors MedE CMS Changhao Xu

‘Smart' Bandages Monitor Wounds and Provide Targeted Treatment

03-24-23

Unlike a typical bandage, which might only consist of layers of absorbent material, the smart bandages are made from a flexible and stretchy polymer containing embedded electronics and medication. The electronics allow the sensor to monitor for molecules like uric acid or lactate and conditions like pH level or temperature in the wound that may be indicative of inflammation or bacterial infection. [Caltech story]

Tags: MedE Wei Gao

Conversations on Artificial Intelligence: The Future of Personalized Medicine

03-20-23

As part of Conversations on Artificial Intelligence, a webinar series hosted by the Caltech Science Exchange, Andrew and Peggy Cherng Professor of Electrical Engineering and Medical Engineering Azita Emami discusses how her lab incorporates artificial intelligence (AI) into medical devices to improve health and enhance quality of life. Watch the conversation. [Caltech story]

Tags: EE research highlights MedE Azita Emami

Knots Smaller Than Human Hair Make Materials Unusually Tough

03-09-23

In the latest advance in nano- and micro-architected materials, engineers at Caltech have developed a new material made from numerous interconnected microscale knots. The knots make the material far tougher than identically structured but unknotted materials: they absorb more energy and are able to deform more while still being able to return to their original shape undamaged. [Caltech story]

Tags: APhMS research highlights MedE Julia Greer Sammy Shaker Weiting Deng Widianto Moestopo

Wavefront Shaping: From Telescopes to Biological Tissue

02-24-23

Researchers, led by Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, have made a major step forward in medical imaging by taking inspiration from the field of astronomy. In astronomy, the light that reaches telescopes is distorted by the earth's atmosphere, resulting in blurry images of planets, satellites, and other cosmic objects. The earth's atmosphere is what's known as a scattering medium; it scatters light, making images appear unfocused and cloudy. Wavefront shaping is a method of generating focused light by reversing the optical distortion caused by the atmosphere. In this method, a reflective device, like a mirror, "shapes" light waves to counterbalance distortion. It's similar to a person wearing active noise-cancelling headphones to combat ambient noise. [Caltech story]

Tags: EE research highlights MedE Lihong Wang

A GPS for Smart Pills

02-13-23

Caltech researchers have developed proxies for human doctors that are small enough to travel through the human body and help diagnose ailments. These "smart pills" are typically swallowed, and as they pass through the digestive tract, they collect health data, record images, and even deliver drugs. [Caltech story]

Tags: EE research highlights MedE Azita Emami Mikhail Shapiro Saransh Sharma

Wei Gao Receives US National Academy of Medicine Catalyst Award

12-05-22

Wei Gao, Assistant Professor of Medical Engineering; Investigator, Heritage Medical Research Institute; Ronald and JoAnne Willens Scholar, has received the 2022 US National Academy of Medicine Catalyst Award in the Healthy Longevity Global Competition. The Global Competition is part of a larger initiative to fuel a worldwide movement to help improve physical, mental, and social well-being for people as they age, known as the Healthy Longevity Global Grand Challenge.

Tags: APhMS honors MedE Wei Gao

Seeing More with a Needle-Shaped Laser

12-02-22

Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering; Andrew and Peggy Cherng Medical Engineering Leadership Chair; Executive Officer for Medical Engineering, and his research team show how they developed a new variant of photoacoustic microscopy (PAM) called needle-shaped beam photoacoustic microscopy (NB-PAM). NB-PAM has a depth of field nearly 14 times greater than what was achievable before. [Caltech story]

Tags: EE research highlights MedE Lihong Wang Rui Cao

New Process Allows 3-D Printing of Microscale Metallic Parts

12-01-22

Engineers at Caltech have developed a method for 3-D printing pure and multicomponent metals, at a resolution that is, in some cases, an order of magnitude smaller than previously possible. "We had to develop a new way of doing it, and we couldn't rely on heat to build our structures," says Max Saccone. [Caltech story]

Tags: APhMS research highlights MedE MCE MCE Julia Greer Max Saccone Rebecca Gallivan Daryl Yee Kai Narita